Veraflox® should not be used dogs during the period of growth as developing articular cartilage may be affected. The period of growth depends on the breed; for the majority of breeds, Veraflox® must not be used in dogs of less than 12 months of age, and in giant breeds less than 18 months.
Do not use Veraflox® in dogs with persisting articular cartilage lesions, since lesions may worsen during treatment with fluoroquinolones.
The safety of Veraflox® has not been established during pregnancy and lactation in dogs, so should not be used.
Veraflox® can be used in kittens aged from 6 weeks of age.
The safety of Veraflox® has not been established during pregnancy and lactation in cats, so should not be used.
All the main veterinary laboratories in the UK have the capability to test pradofloxacin sensitivity. Many include it as part of their standard panel without a request from the veterinary surgeon; e.g. IDEXX laboratories test sensitivity to pradofloxacin for all licensed pathogens as standard. We would advise that when submitting a sample for culture and sensitivity vets ask their laboratory to test sensitivity for pradofloxacin to allow the vet to make an informed choice as to the most appropriate antibiotic for the infection present.
Stickers for submission forms are available from your Territory Manager or via the Bayer Vet Centre. If a laboratory has any specific questions or would like assistance with testing for pradofloxacin susceptibility then advise them to contact the Bayer technical support line.Bayer Vet centre
Veraflox® should not be administered concurrently with antacids, sucralfate, multivitamins or dairy products, as absorption of Veraflox® may be decreased. Seek advice from the Bayer technical team if you have a specific query.
Fluoroquinolones should not be used in combination with non-steroidal anti-inflammatory drugs (NSAIDs) or in animals with a history of seizures because of potential pharmacodynamic interactions in the CNS.
The combination of fluoroquinolones with theophylline could increase the plasma levels of theophylline by altering its metabolism and thus should be avoided.
The combined use of fluoroquinolones with digoxin should also be avoided because of potentially increased oral bioavailability of digoxin.
For any specific queries on Veraflox® administration with other medicines please call the Bayer technical line on 0118 206 3000.
No, when a fluoroquinolone is indicated, Veraflox® is the responsible choice in terms of limiting the development of antimicrobial resistance.1 Using a second generation molecule first may actually select for resistant strains, potentially making the infection more difficult to treat.
Veraflox® has the lowest available MPC when compared to second generation fluoroquinolones and is therefore the responsible choice when a fluoroquinolone is indicated.2
More information on this can be found on the microbiology and MPC focus pages.
Veraflox® also delivers an enhanced spectrum of antimicrobial activity (including Gram-positive and anaerobic bacteria) when compared to other fluoroquinolones.3,4
Veraflox® is not licensed for use in exotics. As there is an enhanced spectrum of activity against gram positive bacteria, it should not be used in hind gut fermenters.
Yes, studies have shown that Veraflox® is very effective at eliminating anaerobic bacteria; including Porphyromonas spp. and Prevotella spp.5-6 These often play a major role in aggressive bone destruction in periodontal disease.
It is the only veterinary fluoroquinolone licensed for the adjunctive therapy of severe infections of the periodontal and gingival tissues.periodontal
Fluoroquinolones, along with other agents such as third generation cephalosporins (e.g. cefovecin, Convenia®) are not considered to be a first line antimicrobial choice in infections. Their use should be reserved for those cases that haven’t responded, or are unlikely to respond to first line therapy. Use should also ideally be based on appropriate culture and sensitivity testing. It is important to use them though when they are indicated as not doing so could have potentially serious outcomes.
BSAVA guidelines state fluoroquinolones should be reserved for when other antimicrobials are inappropriate and/or ineffective, and culture and sensitivity results indicate that they will be effective.7
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